Treatment Marble Bone Disease

This allows the restoration of bone resorption by donor derived osteoclasts.

Treatment marble bone disease.

Osteopetrosis can cause bones to dissolv. Corti costeroids high dose calcitriol have been helpful in the treatment of osteopetrosis. Bone marrow transplant has many risks but if it is successful it saves the life of a child who would otherwise die from complications of the disorder. For patients who have complications surgery may be necessary.

What are treatments for osteopetrosis or marble bone disease. However in cases of children affected with osteopetrosis treatment involves treating complications and improving quality of life. Advertisement in cases of osteopetrosis in adults there are no treatments required. Bone marrow transplant and splenectomy may be useful in some patients.

A recently published article6 reported on the follow up of seven patients with marble bone disease who had received alkaline therapy. Therapeutic agents that can be used to treat marble bone disease include gamma interferon a protein that delays progression of the disease or calcitriol a vitamin d compound that stimulates osteoclasts to dissolve and absorb bone. This treatment resulted in improvement of growth retardation. Bone marrow transplant is the only complete cure available for malignant marble bone disease.

Osteopetrosis literally stone bone also known as marble bone disease or albers schönberg disease is an extremely rare inherited disorder whereby the bones harden becoming denser in contrast to more prevalent conditions like osteoporosis in which the bones become less dense and more brittle or osteomalacia in which the bones soften. Treatment strategies include correcting anemia thrombocytopenia and treating infections. In pediatric childhood osteopetrosis surgery is sometimes needed because of fractures. Optimal transplants require donor marrow from a sibling.

Complications of paget s disease of bone can include broken bones hearing loss and pinched nerves in your spine.